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KMID : 0387920070180020170
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Korean Journal of Cytopathology
2007 Volume.18 No. 2 p.170 ~ p.174
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Imprint Cytology of Granular Cell Tumor -A Case Report-
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Sung Woo-Jung
Choi Joon-Hyuk
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Abstract
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Granular cell tumor is a rare tumor of the soft tissue and this is characterized by proliferation of large cells with granular appearing eosinophilic cytoplasm. We report the imprint cytologic features of a case of granular cell tumor in the left calf of a 52-year-old woman. Microscopic examination showed moderate cellularity. The tumor cells were arranged both as single cells and in clusters. The cells were large polygonal-shaped and they had small round nuclei with finely granular chromatin and occasionally conspicuous nucleoli. The cytoplasm was abundant eosinophilic and granular. Naked nuclei and spindle-shaped tumor cells were occasionally noted. No mitosis and necrosis were present. The background showed cytoplasmic granular materials. The tumor cells showed positivity for S-100 protein. Ultrastructurally, abundant lysosomes were present in the cytoplasm of the tumor cells.
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KEYWORD
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Granular cell tumor, Soft tissue, Cytology, Imprint
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